Civil War - This prophecy predicted war between the northern states and the southern states beginning in South Carolina, and that war will be "poured out on all nations", and that nations will be fighting against other nations, and that "slaves shall rise up against their masters, who shall be marshaled and disciplined for war", and that war will end with "plague, and earthquake" culminating in the "full end of all nations". D&C 87
Four months earlier, Nat Turner led about seventy slaves on a killing spree across the plantations of Southampton, Virginia, leaving fifty-five whites dead, escalating fears that and increasing rhetoric over the slave issue.
[Source: Wikipedia, Prophesies of Joseph Smith, http://en.wikipedia.org/wiki/Prophecies_of_Joseph_Smith,_Jr.; Grunder, Rick, Mormon Parallels: A Bibliographic Source]